After losing 275 pounds, Jennifer Butters has successfully kept it off by creating balance in her life.
Sal Paradiso realized he had to lose weight or he might end up like his father, who died of a heart attack at 42.
Brendan O'Donnell's 30th birthday was a wake-up call. He needed to change his life and get healthy.
At 322 pounds, Erica Lugo felt too exhausted to play with her son. She realized she needed to lose weight and transform her life.
After Brittany Horton was told she was "too big" for health insurance, Horton lost 208 pounds, or more than half her body weight.
By swapping stress eating for exercise, Jacqueline Gilmore-Jackson was able to lose 68 pounds and transform her life.
Losing weight is tough. But losing more than 100 pounds is a great accomplishment. Seven women share what they wish they knew before losing.
Andy Albertson ate to comfort himself, packing on pounds. With hard work, he dropped 176 pounds and transformed his life.
When this couple realized that their weight would prevent them from having a long life together, they got fit and it made them closer.
Shannon Fleming transformed her body with the help of 100,000 steps a week.
Carly Bernard was overweight from an early age. After being bedridden for a week, she knew she had to lose weight and transform her life.
Lauren LaPorta pushed herself to stand and walk again to lose weight.
Before she was 30, NaTasha Glaspy depended on drugs for blood pressure, cholesterol, and diabetes. She shed 160 pounds and ditched the meds.
The Whole30 diet program is often slammed for being too restrictive and not based on independent science. But it's changed my life.
Like lots of other new moms, Betsy Ayala felt depressed when she couldn't lose the baby weight. Here's what she did to turn her life around!
The moment Haley Smith saw her engagement photos, she knew she had to start losing weight.
After using food to cope with tragic loss, a young mother found herself morbidly obese and in need of emotional healing.
Jacqueline Adan hopes others learn from her experience and 'never give up.'
Diane Naylor was a constant dieter, but this time around she made lasting changes that helped her lose over 200 pounds.
When you've spent your entire life overweight, you try to convince yourself that it's just normal.
When Jamie Lanigan realized she needed to lose weight, she had no idea her new job would help.
Andrew Taylor says he feels healthier and happier after his "Spud Fit" challenge, even as nutritionists warn against trying a similar diet.
Hearing she was obese drove Nina Gibson to take action. But she also got some much-needed inspiration from one Dwayne "The Rock" Johnson.
After quitting drinking and cutting out carbs, a Texas woman lost 139 pounds and is inspiring others to live healthier lives.
When Karen Kelly got a dog, her life changed completely — for the better.
How did Rocco DiSpirito drop 30 pounds? A very hearty breakfast, for starters. He shares his morning routine with TODAY.
It's no illusion: Magician Penn Jillette is much slimmer these days. Even he admits the way he started was "very extreme."
Jennifer Moats is emerging from a divorce one husband and 125 pounds lighter. Here's how the lost the weight.
Amid a devastating personal loss, Tina Tait dropped 130 pounds and ran the New York City Marathon. She got a boost of inspiration from TODAY's Al Roker.
Before he knew it, John DiBenedetto's weight had ballooned to 350 pounds. Here are steps he took to lose 185 pounds!
Four years ago, Casey Gemmell decided to get serious about changing her lifestyle. Here's how she did it.
The elementary school cafeteria manager lost 100 pounds after she ate only the meals she was serving to students.
Ask Rachel Graham how she lost almost 100 pounds in one year and the formula is simple.
At just 23 years old, Simone Pretscherer realized she needed to change her life.
Adam Garner used to weigh 488 pounds. Today he is feeling better than ever!
TODAY happily welcomes two new members to the Joy Fit Club!
There was an unexpected side-effect when Jayme Gill fell in love: she gained weight. Now, she's on the right track and shares her advice.
Meet six inspiring people who lost over 100 pounds each in mid-life.
Two women who lost a combined 445 pounds shared their dramatic weight-loss journeys into Joy Bauer's Joy Fit Club with Kathie Lee and Hoda.
TODAY's Yosef Herzog lost 50 pounds in five months. See the transformation that Kathie Lee and Hoda won't stop talking about!