Authorities told E! that "Reed was in the roadway on Lawrenceville Highway near Hamilton Road when struck," and the driver immediately called 911; she was pronounced dead at a nearby hospital at 10:59 p.m. EST.
The driver was "determined to be not at fault," authorities added.
Reed is survived by 10-year-old Tren Brown, her son with rapper Kurupt. Brandi Williams and Shamari Fears-DeVoe, her bandmates from Blacque (with hits like "808") mourned her loss in a joint statement released Saturday.
"We are devastated by the loss of our group member, sister and friend Natina Reed. Because of the enormous support of Blaque fans and our love for each another, Blaque officially reunited this fall and we were in the process of working on a new album and a reality show. Natina continuously embodied the pioneering spirit of Blaque and her undeniable creativity touched the hearts of fans everywhere. Natina was a mother, sister, accomplished songwriter, artist and friend. We ask for your prayers at this time for Natina's family. She will forever be missed and her global influence eternally felt. We thank God for the experiences we shared."
Reed was a protege of TLC's Lisa "Left Eye" Lopes -- who herself passed away in a 2002 car accident.