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TV's Top Couples 2011: Vote in the Sweet 16 Round!

How are you guys going to decide between couples like these?!
/ Source: E!online

How are you guys going to decide between couples like these?!

We're down to the Sweet 16, and we've got matchups like House &Cuddy from House versus Meredith &Derek from Grey's Anatomy, Glee's beloved Brittana versus Fringe's Peter &Olivia, and Castle &Beckett from Castle versus The Vampire Diaries' Delena.

Already know who you want to win? Then get voting!

QUESTIONS? CONCERNS? Talk to @JenniferArrow on Twitter

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This round closes Tue., Feb. 22 at 11 a.m. PST. Thank you for playing, and good luck to you and your fandom!

CLICK: Get our gallery of TV's Top Couples!

WATCH: Jessica Alba is pregnant with baby No. 2!