NBC says Eric Clapton will perform with Bruce Hornsby and his band on Jay Leno's new prime-time show.
Hornsby and the Noisemakers will play "Space is the Place" on "The Jay Leno Show" on Sept. 17. The song is from Hornsby's upcoming album, "Levitate."
Leno has said he intends to offer interesting groupings when he showcases musicians on his new prime-time comedy show. The Sept. 14 debut will include a performance by Jay-Z, Rihanna and Kanye West.
The former "Tonight" host's new show will air at 10 p.m. EDT Monday through Friday.