TODAY's Takeaway: People reveals Most Beautiful; designers make clothes to save lives

Lupita Nyong'o is People's Most Beautiful, Alan Cumming is back on Broadway and Liya Kebede is using fashion for good.

1. Lupita Nyong'o is People's Most Beautiful Person for 2014, the magazine revealed Wednesday morning on TODAY.

The 31-year-old actress, who won an Oscar for her role in "12 Years a Slave," beams from the cover that promises “her inspiring story.”

Also on People’s list: Our own Hoda Kotb!

2. The fashion industry’s top designers have teamed up with a charity fighting to wipe out AIDS among infants in South Africa.

"We're ensuring that every child is born free of HIV, meaning aiming to end mother-to-child transmission of AIDS by 2015," Ethiopian model Liya Kebede told Natalie.

3. Savannah’s living it up on her sun-soaked honeymoon. She revealed in her latest blog post that she’s letting it all hang out on the best vacation of her life.

"I am just going to enjoy the miracle that is pregnancy and be thankful every minute for good fortune, and good guacamole."

Savannah Guthrie on vacation with husband Mike Feldman ... and baby bump makes three! Vacationing while pregnant is an excellent excuse to let it all hang out and not worry about how you look in a bathing suit.

4. The extraordinary Alan Cumming stopped by Studio 1A this morning to chat about his new (old) role in “Cabaret” on Broadway.

"I'm doing kicklines with girls less than half my age (now)," he boasted to Matt.

5. Author and advocate Mary Fisher visited to talk about working with a North Carolina dad and his daughter to make the “100 Good Deeds” bracelet that raises money for women in Haiti and Africa.

And that’s TODAY’s Takeaway!