We just hate when it doesn't work out.
A rep for David Duchovny confirms to E! News that the X-Files star and wife Ta Leoni have separated.
This isn't exactly new territory for the couple. The two spent several months apart in 2008 while the Californication star was in rehab for sex addiction, but reconciled afterward.
Duchovny and Leoni have been married since 1997 and have two children together.