Williams, 55, posted an announcement on Twitter Monday that said she will be taking time off from the show due to fatigue caused by the autoimmune disorder.
"Recently, Wendy has been dealing with symptoms from her Graves' disease which is causing fatigue,'' the announcement reads. "In consultation with her doctor and as a precautionary measure, she will be taking some time off as she continues to receive treatment.
"We look forward to welcoming Wendy back soon and continuing the Wendy@Home shows. More updates on a return date will follow."
This is not the first time Graves' disease has caused Williams to take a break from her show since she revealed in 2018 she has the disorder, which can also cause heart palpitations, tremors, anxiety, irritability and shakiness, according to the Mayo Clinic. Other symptoms include weight loss, fatigue, heat sensitivity and menstrual cycle changes.
Williams took a three-week break from her show in 2018 and then an extended break last year as she dealt with the effects of her condition.
Two months after announcing her hiatus last year, she revealed she had been living in a sober home because of an ongoing battle with drug addiction.