Jeff Rossen lost nearly 30 pounds for a weight-loss challenge for TODAY. After 2 years, he's managed to keep the weight off.
When Karl Burr was almost 600 pounds he was unhappy and his weight made his genetic motor tics worse. In two years, he lost 310 pounds.
After her heart stopped for three seconds when she was only 34, Chasity Davis knew she had to lose weight to save her life.
After years of trying to slim down, Brian Bolduc suddenly had a powerful motivation to lose weight: his mother's life depended on it.
Ten women share what they wish they knew about dieting before they adopted healthy eating habits.
When Natalie Moxey received a Christmas card from her local Indian restaurant, she knew it was time to eat healthier and lose weight.
After Kari Hammond's daughter, Alexa, said she was worried about Hammond's weight, Hammond followed four steps to lose 78 pounds.
By slowly cutting unhealthy foods from his diet and walking, Lou Maldonado started his weight loss journey. In 5 years, he lost 300 pounds.
Leandie Williams shares the secrets to her weight-loss transformation, and recalls the mortifying plane ride that prompted her journey.
After meeting in group exercise classes, these four friends encouraged one another to lose weight and eventually compete in an extreme race.
Lydia Dziubanek was stuck in an unhealthy relationship, overweight, and struggling with depression when she realized she had to change.
When Jenna Winchester turned 17 she knew she needed to make serious changes to her life and lose weight. In 2 years, she lost 200 pounds.
After seeing an unflattering video of herself, Amber Anderson realized she was overweight. In a year, she lost half her body weight.
After a doctor told her she was insulin resistant, 14-year-old Mele Osai knew she had to change her life and lost 143 pounds in 2 years.
When their grandmother told Dillon and Cory Sasvari that she worried about their health, they lost weight together, shedding 342 combined.
After seeing a widely-shared picture of herself, Jordan Kohanim realized she was unhealthy and needed to lose weight.
When Justin Weber first saw his son he realized he had to lose weight to be the father he hoped he would always be.
When we reach our 30s, even the best laid weight-loss plans can be difficult to manage.
Andrea and Ronnie Brower lost almost 600 pounds. When they realized they had so much in common, they knew they were meant to be together.
After a little inspiration from Al Roker, Marcie Jaworski started eating healthy foods and exercising, dropping 171 pounds in a year.
When LeAnne Manuel couldn't fit into the largest graduation gown available she knew it was time to "face her demons with food."
A viral Instagram photo shows what weight loss can really look like ... Extra skin and all.
At only 20-years-old, Chenise Nupp thought she'd never lose weight but by sticking to a low-carb, high protein diet, she shed 110 pounds.
Most weight-loss plans focus on what goes into your stomach, but one of the creators of "The Biggest Loser" says it starts with your head.
After breaking her ankle, Heather Crockett Oram gained 80 pounds. A few years later, she lost 82 pounds in a year and kept it off.
Diana Johnston and Dana Smith will have something extra special to celebrate on Mother's Day: their new bodies.
After reading mean comments about her weight on social media, Harshi Suraweera changed her life and lost 92 pounds in less than a year.
Brian and Erin LeBlanc are enjoying their shrinking bodies and bulging wallets.
After packing on pounds by using comfort food to cope, Patricia Wilson realized she needed to lose weight.
Four years ago, Casey Gemmell decided to get serious about changing her lifestyle. Here's how she did it.
Peggy Pullen was inspired to lose 90 pounds after a cruel comment from an unknowing child at a swimming pool.
When Jacquee Broaddus noticed her sister Jessee Baldwin was losing weight, she changed her diet, too. Together, they've lost 245 pounds.
Seven years ago, Megan McGee was in an unhealthy relationship and turned to food for comfort. Here is how she turned things around.
After losing 275 pounds, Jennifer Butters has successfully kept it off by creating balance in her life.
Sal Paradiso realized he had to lose weight or he might end up like his father, who died of a heart attack at 42.
Brendan O'Donnell's 30th birthday was a wake-up call. He needed to change his life and get healthy.
At 322 pounds, Erica Lugo felt too exhausted to play with her son. She realized she needed to lose weight and transform her life.
After Brittany Horton was told she was "too big" for health insurance, Horton lost 208 pounds, or more than half her body weight.
By swapping stress eating for exercise, Jacqueline Gilmore-Jackson was able to lose 68 pounds and transform her life.
Losing weight is tough. But losing more than 100 pounds is a great accomplishment. Seven women share what they wish they knew before losing.
Andy Albertson ate to comfort himself, packing on pounds. With hard work, he dropped 176 pounds and transformed his life.
When this couple realized that their weight would prevent them from having a long life together, they got fit and it made them closer.