Kathy Griffin forces Ryan Seacrest to kiss her

Julianne Hough better watch her back!

During the red carpet pre-show at Sunday's Primetime Emmy Awards in L.A., Kathy Griffin made a move on the 23-year-old's boyfriend, E! News host Ryan Seacrest.PHOTOS: Emmys 2011 red carpet

"Are you still banging the dancer?" Griffin, 50, asked. "How did you get her? You're with Julianne Hough! And you're...you? What kind of smoke and mirrors game are you playing?"

Seacrest merely laughed and shifted the interview back to Griffin, noting that her lips looked "very, very red."

"Have you left a mark on anyone?" he asked.PHOTOS: Look back at the worst Emmy ensembles of all time

It was then that Griffin — clad in Oscar de la Renta — seized her moment to smooch the TV host. "Oh, gosh," Seacrest, 36, groaned. "I don't really want this tape to exist."

"There," Griffin said. "I just sold my soul to the devil."PHOTOS: See what the stars wore at the 2010 Emmys

As Griffin walked away, Julianna Marguiles stepped in and came to Seacrest's aid, helping him remove the comedian's lipstick with a handkerchief. "I shouldn't be wiping your lips with a white dress on," she laughed.