Majel Barrett-Roddenberry, the wife of “Star Trek” creator Gene Roddenberry, has passed away, Access Hollywood has learned. She was 76.

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The actress died of leukemia at 12:27 AM on Thursday with her son, Rod, by her side. She was diagnosed with the disease six months ago.

Majel, whose acting credits included “Bonanza” and “Leave It To Beaver,” had been a part of “Star Trek” in all of its forms since it first premiered on September 8, 1966.

In addition to playing Number One and Nurse Christine Chapel in the original series, she played Deanna Troi’s mother on “Star Trek: The Next Generation.”

And Majel also voiced the computer of the various starships used throughout all of the TV shows and movies from the sci-fi franchise — she just completed her voiceover work as the voice of the Enterprise in director J.J. Abrams’ reboot of “Star Trek,” due in theaters on May 8, 2009.

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